Doherty, who will be handed Spur’s No. 2 jersey, put pen to paper on a deal keeping at the Tottenham Hotspur Stadium until 2024 on Sunday morning.
Jose Mourinho continues his summer spree as he completes his fourth summer capture with the defender.
Doherty was outstanding with Wolves, as he played a key part offensively and was solid defensively.
After graduating from the youth system of Ireland side Bohemians, Doherty moved to England in 2010, signing for Wolverhampton Wanderers.
He went on to establish himself in the side, helping them to win promotion from League One up to the Apex of English football in his 10-year stay at the Molineux.
Following his superb performance for Nuno Espírito Santo last season, Jose Mourinho was keen on landing the Irishman and had identified him as a replacement for Serge Aurier, who looks set to depart the North London club.
Doherty recorded six goals in 50 appearances for Wolves last season while also setting up four assists for his teammates.
“I’m very proud to be joining such a big club,” Doherty said.
“(They have) the best stadium in the world and possibly the best training ground in the world from what I’ve seen.
“My time at Wolves was fantastic, I haven’t got a bad word to say about the whole club at all.”
Tottenham Hotspur boss Jose Mourinho also revealed that he always believed in the club’s vision and was aware of their rich history.
“My opinion changed for the better, but the idea that I had was already good. With so many years in England, I knew the history, the prestige of the club and the quality of the players.
“Of course, when you see a club building that stadium and this training ground you understand immediately the vision. It was basically what I was waiting for.”
Doherty joins Tottenham for a fee of £15 million as their third summer signing, after the capture of Pierre-Emile Hojbjerg and veteran shot-stopper Joe Hart.